| 姓 名： | 陳健生 (Chien-Sheng Chen, Ph.D) |
| 職 稱： | 副教授 (Associate Professor) |
| 專 長： | 蛋白質體微陣列、 晶片奈米生物感測科技、生醫化學 |
| 電子信箱： | cschen@g.ncu.edu.tw |
| 聯絡電話： | (03) 4227151 ext. 36103 / 36105 (Lab) |
| 辦 公 室： | 科五館 505 室 |
| 實 驗 室： | 科五館 504-1 / 504 室 |
Education
| 2005 - 2007 | Postdoc. |
|
| 2001 - 2005 | Ph.D. | Cornell University |
| 1996 - 1998 | MS | National Taiwan University |
| 1992 - 1996 | BS | National Taiwan Ocean University |
歷年研究計畫
Deciphering the Viral RNA-host Interactions Using Human Proteome Microarrays. NHRI-EX102-10233SC; 2013/1/1~2016/12/31
構建大腸桿菌K1蛋白質體晶片並用以研究大腸桿菌K1與人腦微血管內皮細胞的交互作用 2012 8.1~2015.7.31
Construction of an Escherichia coli K1 proteome chip and its application on the novel assay development for the interaction study between human cells and pathogen proteome NSC: 100-2320-B-008-001-; 2011/8/1 ~ 2012/7/31
Identification of Novel Serological Biomarkers for Bipolar Affective Disorder Using Proteome Chip. 100TMUH-NCU-005; 2011/06/01 ~ 2012/05/30
Investigation of the correlation between Rho-kinase activity and both diabetic clinic parameters as well as therapeutic drugs in diabetic patients. NCU-LSH-100-A-012; 2011/01/01 ~ 2012/03/31
Development of chip-based multiplexed immunoassays using liposomal nanovesicles for female Cervicitis. VGHUST99-G4-1; 2010/01/01 ~ 2010/12/31
Development and application of protein chips for a high-throughput systematic detection of interactions among proteins in cancer cells--Protein chips technology development. NSC 98-2627-M-008-004; 2009/08/01 ~ 2012/07/31
Systematic analysis of secretome network in human cerebrospinal fluid under distinct pain conditions using antibody microarrays. Cathay General Hospital; 2009/1/1 ~ 2009/12/31
Identification of intracellular target proteins of antimicrobial peptides using Escherichia coli K12 proteome chips. NSC: 97-2311-B-019-001-MY2; 2008/03/01 ~ 2009/10/31
Presentations at Professional Meetings
1 Chen C-S (2015) High throughput protein interactome studies using genome-wide proteome microarrays. Invited speaker at International Symposium on Targeted Proteomics at Indian Institute of Technology, Bombay, India.
2 Chen C-S (2015) Human Proteome Array Revealed That hnRNPK Binds and Affects the Accumulation of Mature miR-122. Poster presented at the 14th Human Proteome Organization World Congress, Vancouver, Canada
3 Chen C-S (2015) From Biobank, through Proteome Microarray, to Big Data. Invited speaker at Health Information Technology with Telemedicine 2015, Ho Chi Minh City, Vietnam.
4 Chen C-S (2015) Fabrication and applications of proteome microarrays. Invited speaker at The 3rd EITA-Bio Conference, Taipei, Taiwan.
5 Chen C-S (2015) Autoantibody profiling of MAO-A KO mice using human proteome microarrays-in search of biomarkers for ASD. Oral presentation at The 15th Society of Chinese Bioscientists in America International Symposium, Taipei, Taiwan.
6 Chen C-S (2014) A Human Proteome Microarray Identifies that the Heterogeneous Nuclear Ribonucleoprotein K (hnRNP K) Recognizes the 5’ Terminal Sequence of the Hepatitis C Virus. Poster presented at 2014 FEBS EMBO annual meeting, Paris, France
7 Chen C-S (2014) Development of a Novel Bead-based 96-well Filtration Plate Competitive Immunoassay for the Detection of Gentamycin. Poster presented at the 24th World Anniversary Congress on Biosensors, Melbourne, Australia.
8 Chen C-S (2014) Genome-wide Proteome Microarray Technology: an example of E. coli proteome chips. Invited speaker at BIT’s 7th Annual Protein & Peptide Conference, Dalian, China.
9 Chen C-S (2013) Deciphering genome-wide protein interactions using E. coli proteome chips. Invited speaker at World Gene Convention-2013, Haikou, China.
10 Chen C-S (2013) Deciphering human-microbe proteome interactions using E. coli proteome chips. Poster presented at 2013 HUPO, Yokohama, Japan.
11 Chen C-S (2013) Identification of human-microbe protein interactions using E. coli proteome microarrays. Invited speaker at 2013 KHUPO, Seoul, Korea.
12 Chen C-S (2012) Fabrication of an E. coli proteome microarray and its application on human-microbe interactions. Poster presented at 2012 HUPO, Boston, USA.
13 Chen C-S (2011) Fabrication and Application of an E. coli Proteome Microarray. Invited speaker at 2011 Taiwan-US S&T Workshop for International Collaborative Research, Chungli, Taiwan.
14 Chen C-S (2010) Fabrication of an E. coli Proteome Microarray and Its Applications in Basic and Clinical Researches. Invited speaker at 1st Chinese molecular diagnosis technology conference, Beijing, China
15 Chen C-S (2010) Fabrication and application of an E. coli proteome microarray. Invited speaker at 2010 SBBS Systems Biology and Bioinformatics Symposium, Hsinchu, Taiwan.
16 Chen C-S, Sullivan S, Anderson T, Tan AC, Alex PJ, Brant SR, Cuffari C, Bayless TM, Talor MV, Burek L, Wang H, Li R, Datta LW, Wu Y, Winslow RL, Zhu H, Li X (2009) Identification of novel serological biomarkers for inflammatory bowel disease using E. coli proteome chip. Poster presented at 2009 Systems Biology of Human Disease Conference, Boston, USA.
17 Chen C-S, Sullivan S, Anderson T, Tan AC, Alex PJ, Brant SR, Cuffari C, Bayless TM, Talor MV, Burek L, Wang H, Li R, Datta LW, Wu Y, Winslow RL, Zhu H, Li X (2009) Identification of novel serological biomarkers for inflammatory bowel disease using E. coli proteome chip. Poster presented at The 10th International Conference on Systems Biology, Stanford, California, USA.
18 Chen C-S, Sullivan S, Anderson T, Tan AC, Alex PJ., Brant SR, Cuffari C, Bayless TM, Talor MV, Burek L, Wang H, Li R, Datta LW, Wu Y, Winslow RL, Zhu H, Li X (2009) Identification of novel serological biomarkers for inflammatory bowel disease using E. coli proteome chip. Invited speaker at Conference of Biochip Application in China, Chongqing, China.
19 Chen C-S (2009) Fabrication and application of an E. coli proteome microarray. Invited speaker at 10th Frontier Science Symposium, Chungli, Taiwan
20 Chen C-S, Korobkova E, Chen H, Zhu J, Jian X, Tao S-C, He C, Zhu H (2009) A proteome chip approach reveals new DNA base damage recognition activities in Escherichia coli. Invited speaker at PepCon2009, Seoul, South Korea.
21 Chen C-S, Durst RA (2007) Simultaneous detection of Escherichia coli O157:H7, Salmonella spp. and Listeria monocytogenes with an array-based immunosorbent assay using universal protein G-liposomal nanovesicles. Poster presented at 7th International Conference of Food Science and Technology, Wuxi, China.
22 Chen C-S, Tao S-C, Zhu J, Sullivan S, Anderson T, Tan AC, Li X, Kim KS, Zhu H (2007) Fabrication of an E. coli proteome microarray and its application on human serum profiling. Awarded poster presented at 2007 PepTalk conference, San Diego, CA.
23 Chen C-S, Tao S-C, Zhu J, Rhee JK, Zhu H (2006) Construction and application of E. coli proteome chips. Poster presented at 2006 Symposium of Dissecting Biological Networks & Pathways, Baltimore, MD.
24 Chen C-S, Yao J, Durst RA (2005) Liposome encapsulation of fluorescent nanoparticles: quantum dots and silica nanoparticles. Paper presented at 2005 NSTI Nanotechnology Conference Proceedings, p 206-209, May 8-12, Anaheim, CA.
25 Chen C-S, Durst RA (2004) Protein G-tagged liposomes as universal reagents for immunoassays. Poster presented at 2004 Annual Meeting of Institute of Food Technologists, Las Vegas, NV.
Awards and Honors
2014 Distinguished professor, National Central University 特聘教授
2013 Outstanding research award, National Central University 研究傑出獎
2013 Career Development Grant award, National Health Research Institutes
2010 Excellent advisor award (優良導師獎)
2009 Excellent advisor award
2008 Outstanding new faculty award, National Central University
2007 Poster Award of Protein Arrays, Protein Process Development, and Profiling Proteins at 2007 PepTalk conference
2005 Julian S. Colyer Award, Cornell University
